10% allurar Enrofloxacin
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Bidiyo
Ayyukan Pharmacological
Enrofloxacin babban wakili ne na ƙwayoyin cuta don dabbobin fluoroquinolone.Don Escherichia coli, Salmonella, Klebsiella, Brucella, Pasteurella, Actinobacillus pleuropneumoniae, Erysipelas, Proteus, Serratia marcescens, Corynebacterium pyogenes, Porter's sepsis Bacteria, Staphylococcus aureus, Mycoplasma, rauni, da dai sauransu, suna da sakamako mai kyau akan cutar amosanin jini. da Streptococcus, da raunin tasiri akan kwayoyin anaerobic.Yana da tasirin cutar antibacterial a fili akan ƙwayoyin cuta masu mahimmanci.Tsarin aikin maganin kashe kwayoyin cuta na wannan samfur shine don hana gyrase na kwayan cuta na DNA da tsoma baki tare da kwafin DNA na kwayan cuta, rubutawa da gyarawa da haɗawa.Kwayoyin ba za su iya girma da kuma haifuwa kullum kuma su mutu.
Pharmacokinetics
10% allurar Enrofloxacinyana da sauri kuma gabaɗaya ta hanyar allurar ciki.The bioavailability na wannan samfurin ne 91.9% na aladu da 82% na kiwo.An rarraba shi a cikin dabbobi kuma yana iya shiga kyallen takarda da kyau.Ban da ruwa na cerebrospinal, ƙaddamar da miyagun ƙwayoyi a kusan dukkanin kyallen takarda ya fi na plasma.Hanta metabolism shine yafi cire rukunin ethyl na zoben 7-piperazine don samar da ciprofloxacin, sannan oxidation da glucuronic acid daure.An fi fitar da shi ta hanyar koda (ta hanyar ɓoye tubular renal da tacewa na glomerular), kuma 15% ~ 50% ana fitar da shi a cikin fitsari a sigarsa ta asali.Kawar da rabin rayuwar ya bambanta sosai tsakanin nau'ikan dabbobi daban-daban da hanyoyin gudanarwa daban-daban.Kawar da rabin rayuwa bayan allurar intramuscular shine awanni 5.9 na shanu, awanni 9.9 don dawakai, awanni 1.5 zuwa 4.5 don tumaki, da awanni 4.6 na aladu.
Mu'amala
(1)10% allurar Enrofloxacinana amfani dashi a hade tare da aminoglycosides ko penicillin mai faɗi, wanda ke da tasirin daidaitawa.
(2) ions karfe masu nauyi kamar Ca2+, Mg2+, Fe3+ da Al3+ na iya chelate da wannan samfurin kuma suna shafar sha.
(3) Lokacin da aka haɗe shi da theophylline da maganin kafeyin, yana iya rage adadin haɗin furotin na plasma, wanda ba daidai ba yana ƙara yawan taro na theophylline da caffeine a cikin jini, har ma yana haifar da alamun guba na theophylline.
(4) Wannan samfurin yana da tasirin hana enzymes na miyagun ƙwayoyi na hanta, wanda zai iya rage yawan adadin magunguna da aka yi amfani da su a cikin hanta da kuma ƙara yawan ƙwayar jini.
Aiki da Amfani
Fluoroquinolone antibacterial kwayoyi.Ana amfani dashi don cututtukan ƙwayoyin cuta da cututtukan mycoplasma a cikin dabbobi da kaji
Dosage da gudanarwa
Intramuscular allura: kashi daya, da nauyin 1kg, 0.025ml na shanu, tumaki, da alade;0.025 ~ 0.05ml don karnuka, kuliyoyi, da zomaye.Yi amfani da sau 1 zuwa 2 a rana don kwanaki 2 zuwa 3.
Mummunan halayen
(1) Ragewar guringuntsi a cikin ƙananan dabbobi, yana shafar ci gaban kashi da haifar da claudication da zafi.
(2) Abubuwan da suka shafi tsarin narkewar abinci sun haɗa da amai, rashin ci, da gudawa.
(3) Halayen fatar jiki sun haɗa da erythema, itching, urticaria da kuma ɗaukar hoto.
(4)Alashi, ataxia, da seizure ana ganin lokaci-lokaci a cikin karnuka da kuliyoyi.
Hebei Veyong Pharmaceutical Co., Ltd, an kafa shi a shekara ta 2002, wanda yake a birnin Shijiazhuang na lardin Hebei na kasar Sin, kusa da babban birnin Beijing.Ita babbar sana'ar sayar da magungunan dabbobi ce ta GMP, tare da R&D, samarwa da tallace-tallace na APIs na dabbobi, shirye-shirye, ciyarwar da aka riga aka haɗa da ƙari.A matsayin Cibiyar Fasaha ta Lardi, Veyong ya kafa sabon tsarin R&D don sabbin magungunan dabbobi, kuma shine sanannen masana'antar fasahar kere kere ta ƙasa, akwai kwararrun fasaha 65.Veyong yana da biyu samar sansanonin: Shijiazhuang da Ordos, wanda Shijiazhuang tushe maida hankali ne akan wani yanki na 78,706 m2, tare da 13 API kayayyakin ciki har da Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, da kuma 11 shiri samar Lines ciki har da allura, ko foda bayani. , premix, bolus, magungunan kashe qwari da magungunan kashe qwari, da sauransu.Veyong yana ba da APIs, fiye da shirye-shiryen alamar mallaka 100, da sabis na OEM & ODM.
Veyong yana ba da mahimmanci ga gudanar da tsarin EHS (Muhalli, Lafiya & Tsaro), kuma ya sami takaddun shaida na ISO14001 da OHSAS18001.An jera Veyong a cikin dabarun masana'antu masu tasowa a lardin Hebei kuma yana iya tabbatar da ci gaba da samar da kayayyaki.
Veyong ya kafa cikakken tsarin gudanarwa mai inganci, ya sami takardar shedar ISO9001, takardar shaidar GMP ta kasar Sin, takardar shedar APVMA GMP ta Australia, takardar shaidar GMP ta Habasha, takardar shaidar Ivermectin CEP, kuma ta wuce binciken FDA na Amurka.Veyong yana da ƙwararrun ƙungiyar rajista, tallace-tallace da sabis na fasaha, kamfaninmu ya sami dogaro da goyan baya daga abokan ciniki da yawa ta kyakkyawan ingancin samfur, ingantaccen pre-tallace-tallace da sabis na tallace-tallace, mai tsanani da sarrafa kimiyya.Veyong ya yi dogon lokaci hadin gwiwa tare da da yawa duniya sanannun dabbobi Pharmaceutical Enterprises tare da kayayyakin da ake fitarwa zuwa Turai, Kudancin Amirka, Gabas ta Tsakiya, Afirka, Asiya, da dai sauransu fiye da 60 kasashe da yankuna.
