250 MG Triclabendazole Bolus
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Ayyukan Pharmacological
Pharmacodynamics Triclobendazole na cikin rukunin magunguna ne na benzimidazole, ana amfani da shi musamman don tsayayya da ciwon hanta na Fasciola, kuma yana da tasirin kisa a fili akan Fasciola hepatica na shekaru daban-daban.maganin fulke.Bayan da aka shayar da miyagun ƙwayoyi, yana tsoma baki tare da tsarin microtubule da aikin ƙwayar cuta, Yana hana sakin kwayoyin hydrolytic parasites.Tasirin triclobendazole akan tsutsotsi ya bambanta da maida hankali, kamar manya a ƙananan ƙira (1 ~ 3μg / ml)
Har yanzu miyagun ƙwayoyi yana rayuwa har tsawon sa'o'i 24, kuma aikin yana da rauni sosai a cikin mafi girma taro (10-25μg / ml) na 24 hours;babban taro na 25-50μg / ml ya hana shi gaba daya don 24 hours.Amma yafi kula da tsutsotsi.A 10 μg / ml, duk aikin 24-hour an hana shi.
Pharmacokinetics
Halin bioavailability na triclobendazole yana da yawa.Bayan gudanar da baki na nauyin jiki na 10 mg/kg a cikin awaki da tumaki, maganin plasma kololuwa ya kai 15 μg/ml a cikin sa'o'i 24 zuwa 36, kuma matakan jini na triclobendazole da metabolites sun fi girma.Matsakaicin ƙimar miyagun ƙwayoyi shine sau 5 zuwa 20 fiye da sauran benzimidazole anthelmintics, kuma kawar da rabin rayuwar shine kusan awanni 22.Triclobendazole yana da iskar oxygen da yawa a cikin tumaki da beraye zuwa abubuwan sulfone da sulfoxide, waɗanda ke ɗaure ga albumin kuma suna dagewa a cikin plasma fiye da kwanaki 7.Matsakaicin yawan ƙwayar plasma da ɗaure ga albumin na plasma suna da alaƙa da ɗaukar lokaci mai tsawo na aikin antifascioli.Bayan kwanaki 10 na maganin miyagun ƙwayoyi a cikin tumaki, kusan kashi 95% na maganin ana fitar da su a cikin najasa, 2% ana fitar da shi a cikin fitsari, kuma ƙasa da 1% ana fitar da shi a cikin madara.
Ayyuka da Amfani
Benzimidazole anti-fasciola.Ana amfani da shi musamman don rigakafi da kuma maganin ciwon hanta na Fasciola a cikin shanu da tumaki.
Mummunan halayen
Ba a ga wani mummunan halayen ba lokacin amfani da shi bisa ga kayyade amfani da sashi
Matakan kariya
(1) Nakasassu yayin samar da madara.
(2) Yana da guba sosai ga kifi, kuma ragowar kwandon kada ya ƙazantar da tushen ruwa.
(3) Mutanen da ke fama da rashin lafiyar magunguna su nisanci tuntuɓar fata kai tsaye da shakar numfashi yayin amfani da su, su sanya safar hannu yayin shan magunguna, kuma su hana ci, sha da shan taba.
(4) Wanke hannu bayan shafa
Lokacin janyewa
Kwanaki 56 na shanu da tumaki
Adana
Ajiye a wurin da ke ƙasa da 30 ℃.
Hebei Veyong Pharmaceutical Co., Ltd, an kafa shi a shekara ta 2002, wanda yake a birnin Shijiazhuang na lardin Hebei na kasar Sin, kusa da babban birnin Beijing.Ita babbar sana'ar sayar da magungunan dabbobi ce ta GMP, tare da R&D, samarwa da tallace-tallace na APIs na dabbobi, shirye-shirye, ciyarwar da aka riga aka haɗa da ƙari.A matsayin Cibiyar Fasaha ta Lardi, Veyong ya kafa sabon tsarin R&D don sabbin magungunan dabbobi, kuma shine sanannen masana'antar fasahar kere kere ta ƙasa, akwai kwararrun fasaha 65.Veyong yana da biyu samar sansanonin: Shijiazhuang da Ordos, wanda Shijiazhuang tushe maida hankali ne akan wani yanki na 78,706 m2, tare da 13 API kayayyakin ciki har da Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, da kuma 11 shiri samar Lines ciki har da allura, ko foda bayani. , premix, bolus, magungunan kashe qwari da magungunan kashe qwari, da sauransu.Veyong yana ba da APIs, fiye da shirye-shiryen alamar mallaka 100, da sabis na OEM & ODM.
Veyong yana ba da mahimmanci ga gudanar da tsarin EHS (Muhalli, Lafiya & Tsaro), kuma ya sami takaddun shaida na ISO14001 da OHSAS18001.An jera Veyong a cikin dabarun masana'antu masu tasowa a lardin Hebei kuma yana iya tabbatar da ci gaba da samar da kayayyaki.
Veyong ya kafa cikakken tsarin gudanarwa mai inganci, ya sami takardar shedar ISO9001, takardar shaidar GMP ta kasar Sin, takardar shedar APVMA GMP ta Australia, takardar shaidar GMP ta Habasha, takardar shaidar Ivermectin CEP, kuma ta wuce binciken FDA na Amurka.Veyong yana da ƙwararrun ƙungiyar rajista, tallace-tallace da sabis na fasaha, kamfaninmu ya sami dogaro da goyan baya daga abokan ciniki da yawa ta kyakkyawan ingancin samfur, ingantaccen pre-tallace-tallace da sabis na tallace-tallace, mai tsanani da sarrafa kimiyya.Veyong ya yi dogon lokaci hadin gwiwa tare da da yawa duniya sanannun dabbobi Pharmaceutical Enterprises tare da kayayyakin da ake fitarwa zuwa Turai, Kudancin Amirka, Gabas ta Tsakiya, Afirka, Asiya, da dai sauransu fiye da 60 kasashe da yankuna.
