0.2% DRENCH IVERMECTIN
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Pharmacological mataki
Ivermectinyafi yana da kyau anthelmintic sakamako a kan nematodes da surface arthropods a vivo.Tsarinsa na anthelmintic shine don haɓaka sakin γ-aminobutyric acid (GABA) daga ƙwayoyin cuta na presynaptic, ta haka buɗe tashoshi na chloride mai matsakaicin GABA.Ivermectin kuma zaɓi ne kuma babban kusanci ga tashoshi na glutamate-mediated chloride da ke kusa da rukunin GABA-matsakaici a cikin jijiyar invertebrate da ƙwayoyin tsoka, ta haka yana tsoma baki tare da watsa siginar tsakanin tsokoki na neuromuscular da shakatawa da gurɓatar da ƙwayar cuta, wanda ke haifar da mutuwa ko kora daga jiki.Hanyoyin inhibitory interneurons da motoneurons masu ban sha'awa na C. elegans sune wuraren aikin su, yayin da wurin aiki na arthropods shine haɗin neuromuscular.Har ila yau yana da tasiri a kan arthropods, irin su tsutsotsi, mites, da lice.balagagge Coronaria dentata da m parasites a cikin aladu, kuma yana da matukar tasiri ga Trichinella spiralis a cikin hanji (ba shi da tasiri ga Trichinella spiralis na intramuscularly), kuma yana da tasiri mai kyau akan ƙwayar jinin alade da Sarcoptes scabiei.Ba shi da tasiri a kan trematodes da tepeworms.
Pharmacokinetics
Pharmacokinetics naivermectinbambanta sosai dangane da nau'in dabba, nau'in sashi, da hanyar gudanarwa.Halin da ake samu na allurar subcutaneous ya fi yadda ake gudanar da baki, amma gudanar da baki ya fi saurin shanyewa fiye da allurar subcutaneous.Bayan sha, ana iya rarraba shi da kyau zuwa mafi yawan kyallen takarda, amma ba shi da sauƙi a shigar da ruwa na cerebrospinal.Adadin da aka bayyana a cikin tumaki da aladu shine 4.6 da 4 L / kg, bi da bi.Yana da tsawon rabin rayuwa a yawancin dabbobi, 2 zuwa 7 da kwanaki 0.5 a cikin tumaki da aladu, bi da bi.Wannan samfurin yana metabolized a cikin hanta, yafi hydroxylated a cikin tumaki, kuma yafi methylated a cikin alade.An fi fitar da shi a cikin najasa kuma ƙasa da 5% ana fitar da shi baya canzawa ko azaman metabolites a cikin fitsari.A cikin madatsun ruwa masu shayarwa, 5% na kashi an cire shi a cikin madara.
Mu'amalar Magunguna
Yin amfani da lokaci guda tare da diethylcarbamazine na iya haifar da encephalopathy mai tsanani ko mai mutuwa.
Aiki da amfani
Macrolide antiparasitic kwayoyi.Ana amfani da shi don sarrafa nematode, acariasis da cututtukan kwari na parasitic a cikin tumaki da aladu.
Dosage da gudanarwa
Na baka: kashi ɗaya, 0.1 ml na tumaki da 0.15 ml na aladu da 1 kg na nauyin jiki.
Mummunan halayen
Ba a ga wani mummunan halayen ba lokacin da aka yi amfani da shi bisa ƙayyadadden amfani da sashi.
Matakan kariya
(1) An contraindicated a lokacin lactation.
(2) Ya kamata a yi amfani da shi tare da taka tsantsan a cikin shuka a cikin kwanaki 45 na farko na ciki.
(3) Ivermectin shrimp, kifi da halittun ruwa suna da guba sosai, kuma marufi da kwantena na sauran magungunan ba dole ba ne su gurbata tushen ruwa.
Lokacin janyewa: kwanaki 35 don tumaki da kwanaki 28 don aladu.
Lokacin janyewa
Kwanaki 35 don tumaki da kwanaki 28 don aladu.
Hebei Veyong Pharmaceutical Co., Ltd, an kafa shi a shekara ta 2002, wanda yake a birnin Shijiazhuang na lardin Hebei na kasar Sin, kusa da babban birnin Beijing.Ita babbar sana'ar sayar da magungunan dabbobi ce ta GMP, tare da R&D, samarwa da tallace-tallace na APIs na dabbobi, shirye-shirye, ciyarwar da aka riga aka haɗa da ƙari.A matsayin Cibiyar Fasaha ta Lardi, Veyong ya kafa sabon tsarin R&D don sabbin magungunan dabbobi, kuma shine sanannen masana'antar fasahar kere kere ta ƙasa, akwai kwararrun fasaha 65.Veyong yana da biyu samar sansanonin: Shijiazhuang da Ordos, wanda Shijiazhuang tushe maida hankali ne akan wani yanki na 78,706 m2, tare da 13 API kayayyakin ciki har da Ivermectin, Eprinomectin, Tiamulin Fumarate, Oxytetracycline hydrochloride ects, da kuma 11 shiri samar Lines ciki har da allura, ko foda bayani. , premix, bolus, magungunan kashe qwari da magungunan kashe qwari, da sauransu.Veyong yana ba da APIs, fiye da shirye-shiryen alamar mallaka 100, da sabis na OEM & ODM.
Veyong yana ba da mahimmanci ga gudanar da tsarin EHS (Muhalli, Lafiya & Tsaro), kuma ya sami takaddun shaida na ISO14001 da OHSAS18001.An jera Veyong a cikin dabarun masana'antu masu tasowa a lardin Hebei kuma yana iya tabbatar da ci gaba da samar da kayayyaki.
Veyong ya kafa cikakken tsarin gudanarwa mai inganci, ya sami takardar shedar ISO9001, takardar shaidar GMP ta kasar Sin, takardar shedar APVMA GMP ta Australia, takardar shaidar GMP ta Habasha, takardar shaidar Ivermectin CEP, kuma ta wuce binciken FDA na Amurka.Veyong yana da ƙwararrun ƙungiyar rajista, tallace-tallace da sabis na fasaha, kamfaninmu ya sami dogaro da goyan baya daga abokan ciniki da yawa ta kyakkyawan ingancin samfur, ingantaccen pre-tallace-tallace da sabis na tallace-tallace, mai tsanani da sarrafa kimiyya.Veyong ya yi dogon lokaci hadin gwiwa tare da da yawa duniya sanannun dabbobi Pharmaceutical Enterprises tare da kayayyakin da ake fitarwa zuwa Turai, Kudancin Amirka, Gabas ta Tsakiya, Afirka, Asiya, da dai sauransu fiye da 60 kasashe da yankuna.
